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One Year Later, Thousands Speed Research Using Fox Insight

One year ago, The Michael J. Fox Foundation (MJFF) launched Fox Insight (foxinsight.org) as an online platform for the Parkinson's disease (PD) community to share the information it knows best -- what it's like to live with PD every day. Since that time, the number of individuals enrolled has more than quadrupled from 6,500 to over 27,000 -- and Fox Insight is just getting started. The study aims to recruit hundreds of thousands of people to contribute data.

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Exercise and Parkinson's: Frequently Asked Questions

Many people with Parkinson's wonder how and why to exercise for their disease. In a recent webinar on exercise for Parkinson's and an interview with Fox News, MJFF Patient Council Member and Team Fox athlete Jimmy Choi shared how exercise helps him manage Parkinson's disease (PD). Get inspired by Jimmy, and then get answers to your most commonly asked questions about exercise.

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Trials Testing New Therapies for Parkinson's Symptoms

Several clinical trials are testing new ways to manage Parkinson's symptoms -- from anxiety to constipation to dementia -- but they need volunteers to help assess the safety and efficacy of these treatments.

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Tests for Parkinson's within Reach

Today there are more therapies to slow or stop Parkinson's in human trials than ever before. But those treatments face challenges in proving their effectiveness, and we want to ensure that even more potential therapies enter clinical testing.

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Rising Tide: New Study Finds Prevalence of Parkinson's Increasing

A study released last week by the Parkinson's Foundation found that the prevalence of Parkinson's disease is increasing. By 2030, it's estimated that 1.2 million Americans will be living with the disease.

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New Study Suggests Brain Exercises Could Lessen Gait Freezing

Brain exercises, or cognitive training, could help treat freezing of gait. Freezing of gait is when a person suddenly becomes temporarily unable to move, and their feet feel like they're stuck to the floor.

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Traumatic Brain Injury Increases Parkinson's Risk

A recent study in the journal Neurology found that traumatic brain injury (TBI) is associated with an increased risk of Parkinson's disease (PD). While this link was already known, these results add further supportive evidence.

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New Reports Measure Parkinson's Motor Progression

Two recent papers outline the progression of Parkinson's disease (PD) movement or motor symptoms in distinct study populations. While these findings do not provide an absolute picture of how one person will progress with PD, the results may help researchers design smaller, faster and less expensive clinical trials of new treatments.

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Drug Reverses 'Off' Periods in Phase III Trial

People with Parkinson's disease (PD) who experience "off" periods, times when symptoms return because medication isn't working optimally, soon may have a new treatment option. Sunovion Pharmaceuticals Inc. recently announced positive Phase III results of under-the-tongue apomorphine, which mimics the effect of dopamine, the brain chemical that decreases in PD.

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$24-Million Public-Private Partnership Expands Investigation of Parkinson's Disease

The Michael J. Fox Foundation (MJFF), the National Institutes of Health (NIH) and five life sciences companies today announced a public-private partnership to advance understanding, measurement and treatment of Parkinson's disease. The latest focus of the NIH Accelerating Medicines Partnership (AMP) model, this new AMP PD project will apply cutting-edge technologies to tease apart microscopic differences in the cells of people with Parkinson's disease (PD).

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Nicole Jarvis's Oklahoma Winter Gala Snowballs into Success Year after Year

When Nicole Jarvis, 44, was diagnosed with Parkinson's disease (PD) in her late thirties, she immediately began searching for a way to get involved. As a physician, she was drawn to understanding the scientific side of the disease and her symptoms. Moreover, as a local Norman, Oklahoma resident, she was determined to raise the profile of Parkinson's in her community and to increase resources to support patients' quality of life -- particularly for the estimated 15,000 people with PD in her home state.

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Community Tips for Parkinson's Disease Care Partners

When a loved one is diagnosed with Parkinson's disease (PD), spouses, children and close friends may find themselves transitioning into the role of a care partner. For many with Parkinson's, care partners are an integral part of their support system and care team. For care partners, this may bring questions about how best to support a loved one while maintaining other interests and responsibilities.

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First LRRK2 Drug InN Clinical Trials, Company Files Public Offering

San Francisco-based Denali Therapeutics has raised nearly $250 million in its initial public offering, marking the largest biotech IPO of the year. In announcing terms of the IPO -- a major milestone in the life cycle of any company as it first offers stock options publicly, garnering capital for growth and expansion -- Denali shared it is testing a LRRK2 inhibitor drug in a small trial of control volunteers.

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Parkinson's Protein Levels Stable over Year in Early Disease

Today researchers from the Parkinson's Progression Markers Initiative (PPMI) -- a landmark study to find measures of Parkinson's disease sponsored by The Michael J. Fox Foundation (MJFF) -- published the first results looking at protein levels in spinal fluid in a large, longitudinal cohort. They analyzed cerebrospinal fluid (CSF) from 173 people recently diagnosed with Parkinson's and 112 control volunteers collected at baseline (when they joined PPMI) and six- and 12-month follow-up.

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